APC and colorectal carcinoma: In particular, this analysis showed that miR-424-5p, miR-96-5p, miR-1290, miR-224, miR-133a and miR-363-3p target genes known to play a role in CRC, including BRAF, KRAS, EGFR, APC. Moreover, miR-133a and miR-96-5p regulate the PI3K-AKT signaling pathway, which is known to be associated with CRC progression [75].