Furthermore, GSVA revealed that the low-MLRS group had a stronger correlation with pathways involved in adipogenesis, pancreatic beta cells, and other metabolic processes, while the high-MLRS group exhibited stronger activity in pathways related to E2F targets, inflammatory responses, and various cancer-related pathways, such as DNA repair, the P53 pathway, and epithelial–mesenchymal transition (Figure 4C). The gene discussed is TP53; the disease is cancer.