In contrast, this case involves rapid progression from aortitis to Stanford type A dissection within 48 hours in a newly diagnosed GPA, successfully managed with surgery despite chronic low-dose prednisone use for Crohn’s disease, highlighting the need for early detection using CTA and PR3-ANCA testing to guide rituximab and surgical intervention [2,5,11]. Here, PRTN3 is linked to granulomatosis with polyangiitis.