For AIH, two of the following are required: (i) ALT > 5x the ULN; (ii) positive ASMA or serum immunoglobulin G levels > 2x the ULN; and (iii) moderate or severe periportal or periseptal lymphocytic piecemeal necrosis on liver biopsy [10]. This evidence concerns the gene GPT and autoimmune hepatitis.