It was observed that miRNA-569 expression exhibits a negative correlation with ZEB1. In contrast, NUSAP1 expression positively correlates with ZEB1, suggesting that the miRNA-569/NUSAP1/ZEB1 axis may play an important role in regulating the metastatic and invasive ability of PC cells (137). The gene discussed is NUSAP1; the disease is pachyonychia congenita.