A large number of studies have confirmed that inflammatory indices based on peripheral blood tests, such as the Systemic Immune-Inflammation Index (SII), Neutrophil-Lymphocyte Ratio (NLR), Platelet-Lymphocyte Ratio (PLR), Lymphocyte-Monocyte Ratio (LMR), C-reactive protein (CRP), and albumin (ALB),have significant value in early cancer diagnosis and screening (33), treatment monitoring (34), tumor metastasis and invasiveness (35), and prognostic evaluation (36). The gene discussed is CRP; the disease is cancer.