In this study, we systematically analyzed the difference in FCHSD1 expression in pan-carcinoma, and the association of FCHSD1 expression for cancer clinical stage, molecular typing, immune cell infiltration, molecular function, prognosis, drug sensitivity, etc. Finally, we also explore the role of FCHSD1 in genitourinary cancer, and verify its role in human pan-carcinoma through vitro experiments. Here, FCHSD1 is linked to cancer.