SLC13A5 and type 2 diabetes mellitus: Furthermore, the SLC13A5/Mindy knockout mouse showed resistance to Type 2 diabetes (Birkenfeld et al., 2011), displayed lower blood pressure (Willmes et al., 2021) and a lower heart rate (Willmes et al., 2021) and, under certain circumstances, increased bone elasticity and strength (Zahn et al., 2023).