The HF-EA group demonstrated significant reductions in COX-2 and mPGES-1 levels (P < 0.05), significant reductions in PGF2α levels and the PGF2α/PGE2 ratio (P < 0.01), an increase in PGE2 levels (P < 0.05), and a significant increase in β-EP levels (P < 0.01). This evidence concerns the gene PTGS2 and hydrops fetalis.