A. muciniphila and L. plantarum alleviated SLE in mice by reducing systemic inflammation, lowering IL-6 and IL-17 levels, elevating IL-10, restoring gut barrier integrity, diminishing renal IgG deposition, and enhancing kidney function, likely through immune modulation and gut microbiota regulation (77). This evidence concerns the gene IL17A and systemic lupus erythematosus.