CAMK2G and catecholaminergic polymorphic ventricular tachycardia 1: KN-93, a CaMKII inhibitor, was shown to improve Ca2+ abnormalities in the Ryr2+/R4496C KI mouse model of CPVT1 and CPVT1 (RyR2-E2311D)-iPSC-CMs (Liu et al., 2011b; Di Pasquale et al., 2013).