Despite this, girls/women with VWD and HMB remain undertreated; of 1321 female patients with VWD seen at HTCs from 2011 to 2014, 62% (816/1321) had HMB but VWF was given during menstruation to treat just 13 patients (1.6%).33 The gene discussed is VWF; the disease is von Willebrand disease (hereditary or acquired).