NOX4 and neoplasm: Recent studies have reported that RT disrupts the inherent redox homeostasis of tumor tissues and stimulates tumor cells to produce hydrogen peroxide (H2O2) by upregulating NOX4 protein.[8] Building upon the discovery, we hypothesize that the combination of ORSs with H2O2‐mediated chemodynamic therapy could potentially enhance a long‐lasting radiosensitizing effect for efficient RT‐radiodynamic therapy.