B‐type natriuretic peptides, such as N‐terminal pro‐B‐type natriuretic peptide (NT‐proBNP), are released in response to myocardial wall stress and are well‐established biomarkers for the diagnosis and risk stratification of HF, correlating with disease severity and adverse cardiovascular outcomes.5 The gene discussed is NPPB; the disease is hydrops fetalis.