The association of NT‐proBNP with parameters of the mMIDA score—such as advanced age, symptomatic burden, prevalence of atrial fibrillation, atrial and/or ventricular dysfunction, and right ventricular overload—suggests that NT‐proBNP may provide a more comprehensive, objective, and easily accessible risk assessment, independent of echocardiographic expertise. The gene discussed is NPPB; the disease is atrial fibrillation.