While c-Myc and AKT have both been reported to be involved in pathways associated with sarcoma development, they were not used in the creation of the Kras + HPV + SONIC model, and so their staining pattern was expected to be quite different than that seen in the HPV + SONIC system in conjunction with AKT and c-Myc oncogenes. This evidence concerns the gene KRAS and sarcoma.