Also, when comparing complicated versus non-complicated T2DM groups miR-15b-5p/miR-342-5p/miR 611, miRNA 636/NFKB1/RET/HSPA1B and DDX mRNA levels were significantly increased; however, RB1CC1 mRNA was significantly declined, as in Fig. 3 and Table 4. The gene discussed is AKR1C3; the disease is type 2 diabetes mellitus.