Also when prediabetic versus non complicated T2DM miR-15b-5p/miR-342-5p,/miR611/miR636/NFKB1/IGF1R/RET/HSPA1B and DDX mRNA levels were significantly increased however RB1CC1 mRNA was significantly decreased. This evidence concerns the gene AKR1C3 and type 2 diabetes mellitus.