NFKB1 and type 2 diabetes mellitus: Recent ML models for T2DM stratification prioritize clinical parameters or single biomarkers, neglecting the interplay between molecular dysregulation (e.g., miR-342, NFKB1) and systemic metabolic dysfunction (e.g., albumin creatine ratio, HDLc) or focusing narrowly on single omics layers (genomic or proteomic) without integrating multi-dimensional biological data.