The levels of FGL1 in DCDC2-overexpressed ICC cells were remarkably enhanced in mRNA levels (Fig. 4J), in intracellular protein levels (Fig. 4K), and in supernatant (Fig. 4L), drawing forth the hypothesis that FGL1-regulating CD8+ T cells might be deeply involved in the DCDC2-mediated anticancer immune response in ICC. The gene discussed is CD8A; the disease is intrahepatic cholangiocarcinoma.