The prediction model for malignancies compared with infections used the following equation: − 2.8 + (1.1 × arthritis) + (1.1 × duration of fever 15–30 days) + (3 × duration of fever > 30 days) + (− 2.1 × cough) + (1.7 × splenomegaly) + (1.4 × lymphadenopathy) + (2.2 × Hb < 7 g/dL) + (2.3 × platelet count < 150,000 cells/mm3). The gene discussed is GSTM1; the disease is Splenomegaly.