The role of NF-κB in tumors is very complex, as on one hand it can support an anti-tumor microenvironment and assist T cells and NK cells in tumor defense, while on the other hand its cell-intrinsic activity protects tumor cells from apoptosis (Riedlinger et al, 2018; Taniguchi and Karin, 2018). Here, NFKB1 is linked to neoplasm.