NFE2 and Venous thrombosis: While an age older than 65 years (HR: 3.27[1.29–8.45]), arterial hypertension (HR: 2.72 [1.11–6.67]), and NFE2 mutations (HR: 6.39 [2.16–18.90]) were associated with the occurrence of arterial thrombosis during follow up, only prior venous thrombosis (HR: 3.70 [2.11–6.48]) was associated with venous thrombotic events during follow-up (Supplementary Fig. S2).