Each doubling in NT‐proBNP was associated with a 37% relative increase in the primary endpoint of hospitalization for HF or CV death (hazard ratio [HR], 1.37; 95% confidence interval [CI], 1.34–1.41), which was consistent across baseline eGFR categories (P‐interaction = 0.42). The gene discussed is NPPB; the disease is hydrops fetalis.