CD14 and asthma: In both CD14+ monocytes and B cells we found significant time × severity interactions for “allograft rejection” pathways and in CD14 monocytes for “graft-versus-host disease,” “asthma,” “type 1 diabetes,” and “systemic lupus erythematosus.” Examination of the genes that make up these pathways revealed that these signals were largely driven by distinct temporal patterns of HLA expression.