Notably, identifying who should be offered a cancer genetic testing in the Asian community remains challenging as the currently available guidelines for testing have been shown to omit at least 20% of patients carrying BRCA mutations from being tested [21], suggesting the testing criteria on BRCA1 and BRCA2 germline mutations which have been well established in the Caucasian population were not readily applicable to the Asian population. The gene discussed is BRCA2; the disease is cancer.