BRCA1 and breast cancer: In the SEA region, the mutation spectrum of BRCA1 and BRCA2 genes in breast cancer has been studied in Singaporean [18,19,29–31], Malaysian [21,32–37], Filipino [38,39], Vietnamese [40,41], Thai [42,43], and Indonesian [44,45] populations leading to the discovery of novel pathogenic variants from different ethnicities, suggesting that mutation spectrum of the BRCA1 and BRCA2 genes are still understudied in the region.