One of the strengths of our study is that we compare the overall risk factors of fibrosis between individuals with significant and non-significant fibrosis in both lean and obese MAFLD using LSM, the results showed that L-MAFLD patients had a lower value of hepatic steatosis and degree of fibrosis compared to obese-MAFLD, however, using FIB-4, L-MAFLD had a higher degree of fibrosis, this higher value could be due to that L-MAFLD were more older than obese-MAFLD and having lower platelet count and ALT despite they were within the normal limits. The gene discussed is GPT; the disease is fatty liver disease.