TNFSF10 and neoplasm: Finally, applying up-to-date technologies combining ultrahigh-frequency US and PAI, we showed that scDb-hERG1-β1-TRAIL has a good antineoplastic efficacy in TNBC mouse models, producing a strong reduction in tumor growth with the induction of cell death with the occurrence of intratumoral necrosis which occurs even in relatively small tumor masses.