Overexpression of JAK1, TYK2, MAP2K1, IFNG, TRPM2, and ADCY9 significantly inhibited viral infection, whereas overexpression of SNX27, GATA4, EHMT2, PCBP2, SMARCA4, and SLX4 enhanced viral infection (Fig. 1C). The gene discussed is SLX4; the disease is viral infectious disease.