rTMS alleviated cognitive impairments and AD‐like pathology, reducing pTau, APP, Aβ, and PP2A expression. Enhancement of BDNF‐TrkB signaling and increase in hippocampal autophagic activity, as indicated by a higher LC3II/LC3I ratio and a significant reduction in ApoE and p62. This evidence concerns the gene APP and Cognitive impairment.