No evidence for structural brain damage and cognitive impairment: no increase in GFAP, nor cognitive deficits in spatial learning and memory (as assessed in the Morris water‐maze task) or in olfactory‐cued short‐term memory performance (as assessed in the social discrimination procedure). Increased activation of the alpha‐secretory non‐amyloidogenic APP pathway and release of sAPP. This evidence concerns the gene GFAP and Cognitive impairment.