Under the control of an eukaryotic promoter, it enables the production of MAM directly by the host.16 Additionally, a luciferase reporter assay targeting the NF-κB pathway was also performed, demonstrating MAM anti-inflammatory activity in DNBS (Dinitrobenzene sulfonic acid) and DSS (Dextran Sodium Sulfate)-induced colitis models.11,16. This evidence concerns the gene NFKB1 and colitis.