In previous studies, MAM peptides demonstrated significant anti-inflammatory properties in various colitis murine models and in in vitro assays.11,16,17 The activity of MAM was primarily tested by plasmid transfection encoding the entire protein in epithelial cell lines.12 These studies revealed MAM’s capacity to inhibit the NF-κB pathway in a dose-dependent manner. This evidence concerns the gene SGCG and colitis.