Such disturbances in the circadian clock have been associated with a range of health issues, including cancer, cardiovascular diseases, neurodegenerative disorders, and dysfunctions of the liver, kidneys, and musculoskeletal system (Zhou et al., 2014; Wang et al., 2018; Amidi and Wu, 2022; Belloir et al., 2022). The gene discussed is CLOCK; the disease is cardiovascular disorder.