At initial examination, the patient presented with severe elevated blood pressure (BP) (235/156 mmHg), severe hemolytic anemia (Hb 8.4 mg/dL), acute renal failure (urea 176 mg/dL and creatinine 8.49 mg/dL), but no thrombocytopenia (platelet 189,000/μL). The gene discussed is GSTM1; the disease is acute kidney injury.