Infection with both isolates resulted also in up-regulation of genes coding for two receptors sensing RNA (DDX58 and IFIH1), as well as the related regulator DHX58. For DDX58, statistical significance was observed only for 26544/OG10 (p = 0.004742) and a tendency was detected in infection with NH/P68 (p = 0.081272). The gene discussed is IFIH1; the disease is infection.