Based on the expression of related proteins detected by IHC, Hans classification system divided DLBCL into the following Germinal Center B-cell-like(GCB) type: CD10(+) or CD10(-), BCL6 (+)/MUM-1(-), and non-Germinal Center B-cell like(non-GCB) type: CD10(-), BCL6 (+), MUM-1 (+) or CD10(-), BCL6 (+) (20), non-GCB type DLBCL is often considered to be associated with poor prognosis (21). Here, BCL6 is linked to diffuse large B-cell lymphoma.