Among these, the GRIN2A gene, encoding the GluN2A subunit of the NMDAR, has emerged as a significant contributor to disorders such as schizophrenia (Singh et al., 2022; Trubetskoy et al., 2022) and the epilepsy spectrum (Lemke et al., 2013; Samanta, 2023). The gene discussed is GRIN2A; the disease is epilepsy.