OIP5 and endometrial cancer: In endometrial cancer, distinct regulatory mechanisms have been reported: one study demonstrated that OIP5-AS1 sponges miR-200c-3p to modulate the PTEN/AKT pathway, thereby inhibiting cell proliferation and invasion (Liu et al., 2021), while another showed that OIP5-AS1 targets miR-152-3p to upregulate SLC7A5, promoting tumor cell development (Liang M. et al., 2021).