The regression equation for AP prediction probability is as follow: P(AP) = −4.056 + 0.145 * age + 0.547 * NIHSS score −0.413 * hyperlipidemia + 1.007 * hyperhomocysteinemia + 0.146 * cardiac insufficiency + 0.207 * CRP + 0.759 * WBC + 0.949 * NE% + 0.318 * Hb + 0.557 * FBG + 0.179 * PA + 0.214 * BNP + 0.296 * Na+. The gene discussed is NPPB; the disease is hyperhomocysteinemia.