MRC1 and ischemic stroke: A study A study found that rTMS inhibited pro-inflammatory M1 activation (Iba1/CD86) and ameliorated anti-inflammatory M2 activation (Iba1/CD206) in the peri-infarct zone of ischemic stroke mice, and improved motor dysfunction and neuroinflammation after brain injury in mice by modulating microglial cell polarization (32).