In cancers such as THYM, UVM, MESO, PRAD, COAD, READ, KICH, UCS, LGG, OV, KIRP, LIHC, BRCA, BRCA-LumA, BRCA-LumB, and SARC, ADM exhibited strong positive correlations with almost all immune-related genes, including BTLA, BTN2A1, CD160, CD200, CD200R1, CD209, CD226, CD244, CD276, CD28, CD40, CD48, CD86, CTLA4, PVR, TIGIT, TNFRSF18, TNFRSF9, TNFSF14, TNFSF18, CD27, CD274, CD70, CD96, ICOS, TNFRSF25, TNFRSF4, TNFSF9, TNFSF15, HHLA2, TNFRSF14, CD47, and PDCD1. Here, CD28 is linked to cancer.