IFNG and infection: The reduction in characteristic Th2 immunity following influenza virus infection is paralleled with heightened levels of IFN-γ and CD8+ T cells.51, 52, 53 After allergic patients are attacked by influenza, their bodies may prioritize fighting against the influenza virus rather than triggering allergic reactions, shifting from Th2 dominant to Th1 dominant responses, which may reduce allergic reactions during infection.