In ESCC, miR-200b suppresses cell growth and induces cell cycle arrest by modulating expression of cell cycle regulator genes and the Wnt/β catenin signaling pathway [30], and the miR-200 family post-transcriptionally suppresses ZEB1 and ZEB2, which are crucial EMT activators in various types of cancers [31,32]. This evidence concerns the gene ZEB2 and cancer.