ESRP1 and neoplasm: Additionally, wound healing and Transwell assay indicated that silence of ESRP1 promoted the invasive and migrative ability in MKN45 cells (Fig. 2D, E), while overexpressing ESRP1 suppressed tumor invasion and migration in MKN45 cells and SUN484 cells (Fig. 2F, G and Fig. S2E, F).