IL-8, IL-13, and MCP1MCAF were significantly higher in saliva compared to serum in JIA-TMJ while IL-9, Eotaxin (CCL11), IP-10, PDGF-BB, MIP1b, RANTES, and TNF were lower in saliva (Table 6). Here, CXCL8 is linked to juvenile idiopathic arthritis.