Integration of the genomic36,37, transcriptomic38, and proteomic39 data obtained for cancer cell lines of the CCLE and stored in the DepMap database40 showed that both the transcript and protein abundance of p62 increase with aneuploidy score, which is defined as the number of chromosome arm-level aberrations41 (Fig. 1h, i). The gene discussed is SQSTM1; the disease is cancer.