On the contrary, treatment with sub-lethal doses of taxol did not increase the efficacy of PARPi treatment in HCC-1937 and slightly decreased it in uWB1.289 (Supplementary Fig. 5e–h), confirming a requirement for dynamic microtubules in the PARPi-sensitivity of BRCA1-deficient cells. The gene discussed is BRCA1; the disease is hepatocellular carcinoma.