The other 11 features are risk factors for melanoma skin cancer, including CD14+ CD16− monocyte, CD25++ CD45RA− CD4 not regulatory T cell absolute count, activated CD4 regulatory T cell absolute count, CD39+ CD8+ T cell absolute count, CCR2 on myeloid dendritic cell, CD127 on CD45RA+ CD4+ T cell, CD11c+ monocyte, CD3 on central memory CD8+ T cell, CD4+/CD8+ T cell, CD3 on HLA DR+ CD4+ T cell and CD4-CD8− T cell (Table 3 and Figs. 3 and 4). The gene discussed is ENTPD1; the disease is skin neoplasm.