For instance, a paper from 201931 found syndecan‐1 (SDC‐1) on the surface of EVs in plasma from high‐grade glioblastoma multiforme (GBM) patients, where SDC‐1 was used to distinguish high‐grade from low‐grade GBM (Chandran et al. This evidence concerns the gene SDC1 and glioblastoma.