A large number of these genes have been linked in past TWAS to body height (ABTB3, ADAM17, ANGPT1, DSP, HDGFL3, KIFBP, LASP1NB, NKD1, PLVAP, TMEM38A, ZNF417, ZNF44), weight and BMI (ABTB3, ADAM17, ANGPT1, C12orf76, HDGFL3, KIFBP, NOG, PLVAP, SLC4A10), blood pressure and hypertension (C12orf76, CTTNBP2NL, SLC16A1, SLC4A10, TRIM39), lung functioning (DSP, LASP1NB) and to chronological age (ADAM17, CDKN2B, METTL9). The gene discussed is ADAM17; the disease is Hypertension.