The UDG concentrations in colorectal cancer cells (HCT116: 670.5 U/L, SW480: 519.6 U/L) were significantly higher than those in the non-cancer cell line HEK293T (17.9 U/L) and normal colon mucosal epithelial cells NCM460 (14.4 U/L) (Figure S8E). Here, UNG is linked to colorectal cancer.