There are some narrative reviews about the impact of CD36 on different types of cancer, which include AML, such as those reported by Wang et al.,34 Guerrero-Rodríguez et al.,15 and Feng et al.35Some authors described studies that did not comply to the inclusion criteria, for instance, the study by Ye et al.36demonstrated that leukemia stem cells with a higher CD36 expression seemed to be resistant to different chemotherapy drugs, such as cytarabine, doxorubicin, etoposide, SN38, and irinotecan. This evidence concerns the gene CD36 and cancer.