We also examined associations with NT-proBNP using summary statistics from a cohort of 33 043 individuals from the UK Biobank Pharma Proteomics Project (UKB-PPP30; mean age, 59 years and similar to the whole UK Biobank cohort in terms of comorbidities) and a cohort of 35 559 Icelandic individuals from the deCODE+Icelandic Cancer Projects (ICP),31 mean age 55 years with a variety of comorbidities. This evidence concerns the gene NPPB and cancer.