CD40LG and dengue disease: The pooled prevalence of positive results for dengue or dengue antibodies in these patients was 21% (95% CI: 9–36%; 2022 participants; 5 studies; I2 = 98%, p < 0.01) for IgG ELISA (Fig 2) [17,19,29,30,35], 16% (95% CI: 11–21%; 10,891 participants; 10 studies; I2 = 97%, p < 0.01) for IgM ELISA (Fig 3) [17,19,25,29,30,33–37], 19% (95% CI: 09–31%; 2086 participants; 5 studies; I2 = 98%, p < 0.01) for NS1 ELISA (Fig 4) [17,19,25,29,30], and 20% (95% CI: 13–28%; 3107 participants; 9 studies; I2 = 96%, p < 0.01) for RNA PCR (Fig 5) [19,25–29,31–33].